Kopplingsanalys

I mars 2007 blev jag filosofie doktor (PhD) i matematisk statistik vid Lunds universitet; min avhandling behandlar ämnet kopplingsanalys (linkage analysis) vilket i sin tur är en del inom forskningsområdet statistisk genetik. Nedan följer en del länkar till olika artiklar/skrifter som jag har färdigställt (ibland tillsammans med andra) - såväl publicerade som opublicerade - inom detta ämne:

2001:

I. Conditional Two-Locus NPL-Analysis:
Theory and Applications
(Examenarbete; Masters' thesis)
http://angquist.se/lars/mt.pdf

2003:

II. Kopplingsanalys - ett led i forskningen kring
folksjukdomars uppkomst
(Populärvetenskaplig uppsats; kommunikationsteknik)
http://angquist.se/lars/popular.pdf

2004:

III. Using Importance Sampling to Improve Simulation
in Linkage Analysis
(Artikel publicerad i Statistical Applications in Genetics and Molecular Biology;
med Ola Hössjer)
http://www.bepress.com/sagmb/vol3/iss1/art5/

2005:

IV. Improving the Calculation of Statistical Significance
in Genome-Wide Scans
(Artikel publicerad i Biostatistics; med Ola Hössjer)
http://biostatistics.oxfordjournals.org/cgi/content/abstract/kxi025?ijkey=unyZqzzpFh90ys2&keytype=ref

V. Unconditional Two-Locus NPL Analysis
(Teknisk rapport; med Dragi Anevski/Holger Luthman)
http://angquist.se/lars/tr3.pdf

VI. Some Comments on the NPL-Score Distribution
(Artikel)
http://angquist.se/lars/npldist.pdf

2006:

VII. Some Notes on the Choice of Score Function
in NPL Analysis
(Artikel)
http://angquist.se/lars/notessf.pdf

VIII. NPL Analysis: The Fuzzy P-value Distribution Extended
to Multiple Score Functions
(Artikel)
http://angquist.se/lars/fuzzy.pdf

IX. A Discussion on Evidential Interpretation
of Two-Locus NPL Analysis
(Artikel)
http://angquist.se/lars/evidence.pdf

2007:

X. NPL-analysis: The Maximum Selected Pedigree
Subset-Score Method
(Artikel)
http://angquist.se/lars/maxscore.pdf

XI. Pointwise and Genomewide Significance Calculations
in Gene Mapping through NPL Analysis:
Theory, Algorithms and Application
(avhandling; PhD Thesis)
http://www.lu.se/o.o.i.s?id=12588&postid=548075

XII. A Survey of NPL Analysis and Related Issues
(avhandlingsintroduktion)
http://angquist.se/lars/dtintro.pdf

XIII. Pointwise and Genomewide Significance Calculations
in Gene Mapping through NPL Analysis:
Theory, Algorithms and Application
(Artikel publicerad i Qvartilen)
http://angquist.se/lars/dtqvartilen.pdf

2008:

XIV. A Unified Discussion on the Concept of Score
Functions Used in the Context of NPL Analysis
(Artikel publicerad i Bioinformatics and Biology Insights)
http://www.la-press.com/a-unified-discussion-on-the-concept-of-score-functions-used-in-the-con-a558

XV. Strategies for Conditional Two-Locus NPL Analysis
(Artikel publicerad i Human Heredity; med Ola Hössjer/Leif Groop)
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowFulltext&ArtikelNr=126049&Ausgabe=236415&ProduktNr=224250

XVI. A Somewhat Subjective Introduction to
Gene Mapping Through NPL Analysis
(Bokkapitel i Genetic Recombination Research Progress; Nova Science)
https://www.novapublishers.com/catalog/product_info.php?products_id=7070

Fotnötter: (i) Eventuellt nya poster inkluderas efter hand.
(ii) NPL = Nonparametric Linkage